{"version":1,"type":"story","url":"https://digestai.news/story/leash-bio-releases-minos-an-ai-playground-for-lab-in-the-loop-simulati","json":"https://digestai.news/story/leash-bio-releases-minos-an-ai-playground-for-lab-in-the-loop-simulati.json","markdown":"https://digestai.news/story/leash-bio-releases-minos-an-ai-playground-for-lab-in-the-loop-simulati.md","slug":"leash-bio-releases-minos-an-ai-playground-for-lab-in-the-loop-simulati","headline":"Leash Bio releases Minos, an AI playground for lab-in-the-loop simulations","summary":"The tool enables agents to perform **verifiable scientific reasoning** using **tens of thousands of lab-in-the-loop simulations** derived from the company’s proprietary data on **DNA Encoded Libraries (DELs)**—a high-throughput method for studying protein-ligand interactions. The project emerged from an earlier AI playground experiment mentioned in a podcast interview with **Ian Quigley**, Leash Bio’s founder, where the team explored how LLMs could analyze **structure-activity relationships (SAR)** in plain English across **6.5 million molecules** with a budget of **100 simulations per molecule**.","keyPoints":["Minos enables AI agents to simulate **tens of thousands of lab-in-the-loop experiments** using Leash Bio’s DEL data","Built on **Hermes**, a model trained only on Leash’s internal datasets, matching public benchmarks like Boltz"],"whyItMatters":"Minos bridges AI and wet-lab biology by validating hypotheses computationally, potentially cutting drug discovery cycles. Its open tools may democratize high-throughput reasoning for researchers outside Leash’s specialized workflows.","category":{"slug":"research","name":"Research","url":"https://digestai.news/category/research"},"entities":{"companies":["Leash Bio"],"models":["Hermes","Minos"],"people":["Ian Quigley"]},"firstPublishedAt":"2026-10-14T20:35:09Z","updatedAt":"2026-10-14T20:35:09Z","sourceCount":1,"hasPrimarySource":false,"sources":[{"outlet":"Latent Space","title":"Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio","url":"https://latent.space/p/lab-in-the-loop-at-compute-speed","publishedAt":"2026-10-14T20:35:09Z","type":"newsletter","primary":false,"lead":true}],"sourceNotes":null,"discussions":[],"thread":null,"cite":{"text":"Digest AI, \"Leash Bio releases Minos, an AI playground for lab-in-the-loop simulations\", 14 October 2026, https://digestai.news/story/leash-bio-releases-minos-an-ai-playground-for-lab-in-the-loop-simulati","publisher":"Digest AI","title":"Leash Bio releases Minos, an AI playground for lab-in-the-loop simulations","datePublished":"2026-10-14T20:35:09Z","url":"https://digestai.news/story/leash-bio-releases-minos-an-ai-playground-for-lab-in-the-loop-simulati"},"generatedBy":"Written by Digest AI's editorial model from the linked sources; the sources are the record.","license":"Headlines, digests and key points are written by Digest AI and may be quoted with a link to the story page. Linked articles belong to their publishers. Terms: https://digestai.news/terms#reuse"}