DigestAI news desk

Cut through the AI noise.

Model · AI model

Seal

Seal is an AI model from Troyanskaya lab / Flatiron Institute, first covered on 15 October 2026. It is available as open weights you can download and run.

Last updated

Quick facts

Who makes Seal?
Seal is made by Troyanskaya lab / Flatiron Institute.
When was Seal released?
The first report of Seal's release that Digest AI covered was published on 15 October 2026. Researchers introduce Seal AI model for gene regulation in developing human brain →
Are Seal's weights open?
Yes. Seal is released as open weights that can be downloaded and run.
Where is Seal available?
Seal is available as open weights that can be downloaded and run. github.com/FunctionLab/Seal ↗

Taken from the coverage, not from our own testing. A question is left out when none of the reports we read gave the answer. All tracked models →

1 story about Seal

  1. Research new

    Researchers introduce Seal AI model for gene regulation in developing human brain

    A team led by Y. Hao and O. G. Troyanskaya published Seal, a transfer-learning framework that predicts gene expression and variant effects across 26 brain regions, 30 cell types, and 7 developmental stages. Seal links…

    1 source primary source
    Nature Machine Learning