Benchling secures multi-tenant AI agents with Amazon Bedrock AgentCore
Benchling runs AI‑generated scientific code for thousands of life‑science tenants using Amazon Bedrock AgentCore Code Interpreter in VPC mode. The architecture processes more than 600 code execution sessions per day and serves over 250 distinct tenants each week, all while reporting zero security incidents since its early‑April 2026 launch.
Key points
- Benchling runs >600 AI code sessions daily for >250 tenants weekly using AgentCore in VPC mode.
- Architecture isolates untrusted code in a separate AWS account with DNS Firewall, VPC endpoints, and per‑job STS credentials.
- Since early April 2026, Benchling reports zero security incidents and no cross‑tenant data leakage.
The solution isolates untrusted code in a dedicated AWS account separate from Benchling’s production environment. Network isolation is enforced with a VPC that has no internet or NAT gateway, a dedicated security group, Route 53 Resolver DNS Firewall (deny‑list, allow‑list, catch‑all), VPC endpoint policies for S3 access, and NACLs that limit traffic to port 443. Per‑job credentials are injected via AWS STS, ensuring each session can only reach the specific tenant’s data bucket. Continuous integration tests simulate DNS tunneling, unauthorized endpoint connections, and out‑of‑scope S3 requests to validate the defenses.
Benchling’s security team chose this managed approach over building a custom sandbox, citing reduced engineering effort and the ability to focus on product security. Jeremy Stashewsky, Application Security Engineer at Benchling, said the pattern lets them “buy instead of build” a secure, scalable AI execution environment.
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How Benchling secured multi-tenant AI agents with Amazon Bedrock AgentCore
AWS Machine Learning Blog · 21 September 2026
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