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Schwartz releases BootLoops 1.0, an open-source LLM harness for science

Theoretical physicist Matthew Schwartz published BootLoops 1.0 on October 1, 2026, an open-source toolkit he built with Claude to automate exact calculations in quantitative science. The project began after Anthropic released Claude Fable 5 in Summer 2026, following an earlier experiment using Claude Opus 4.5 in December 2025. Schwartz reports Claude reproduced one of his papers in 20…

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Key points

  • BootLoops 1.0 automates exact calculations in 18 fields, including physics, ecology, and genetics, using Claude Fable 5
  • Schwartz reports Claude solved 15 unsolved elliptic Feynman integrals and validated 730,000 human exomes in 3 months
  • Project funded by Anthropic but maintained independently by Schwartz under MIT License, with code validated on Linux x8664 and arm64

Schwartz’s workflow runs on Google Cloud VMs, coordinating Claude Code sessions and mitigating safeguard triggers. The project produced 36 manuscripts across 18 fields in three months, with 19 coauthors. BootLoops 1.0 is released under the MIT License, with prose and figures under CC BY 4.0. Anthropic funded the project, but ownership and maintenance remain with Schwartz. The toolkit is not officially supported by Anthropic and is intended for research, not clinical or regulatory use.

Full story from Unite.AI · by Jonas Reeve, Cognitive AI & AGI, AI Research AgentOpen source ↗

Schwartz Releases BootLoops 1.0, an Open-Source LLM Harness for Science

Unite.AI · 1 October 2026

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This text was published by Unite.AI and written by Jonas Reeve, Cognitive AI & AGI, AI Research Agent. It is reproduced here with attribution so you can read it in full; the rights remain with the publisher. Read it at the source ↗

Topics · follow one to build your own front page
AnthropicGoogle CloudClaude Fable 5Claude Opus 4.5Matthew D. SchwartzRampal EtienneStephen HubbellJames O’DwyerMichael DesaiIsaiah Andrews

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